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Home arrow The CEINGE arrow Investigators arrow Salvatore Francesco
Salvatore Francesco Print E-mail

Foto Francesco Salvatore

Born in Naples, Italy, graduated (M.D.) from the University of Naples in Medicine and Surgery in 1956. He was appointed Full Professor in 1967, and now holds the Chair of Human Biochemistry at the School of Medicine of the University of Naples Federico II.

He served as Director of the Institute of Biochemistry (University of Naples Federico II) from 1972 to 1982, Director of the Department of Biochemistry and Medical Biotechnologies from 1994 to 1995, and Director of the Post-graduate School in Biochemistry and Clinical Chemistry from 1990 to 1996 and from 2006 onward.

From 2000 to 2006 he has been member of Scientific Committee of the Biotechnology Faculty; from 2006 to date he has been President of the Graduate School in Human Nutrition, Health-related Biotechnologies, Graduate Schools in Medical, Pharmaceutical and Veterinary Biotechnologies.

Since 2001 he is Scientific Director of the University and Research Ministry acknowledged Excellence Centre for Biomedical and Biotechnological Studies at University of Naples "Federico II".

Since 1984 he is President and Scientific Director of CEINGE-Biotecnologie Avanzate. CEINGE is an entirely public non-profit Research Centre where, at the moment, about 250 persons are employed both as researchers and as technology transferral specialists (over 12 advanced technological platforms), in the field of genomics and post-genomics, particularly regarding genetic diseases and molecular oncology.

He is also Professor and Member of the Academic Council of the European School of Molecular Medicine [SEMM] (President: Prof. U. Veronesi), instituted by the Ministries of Health, of the University and Research, and of the Treasury in Milan and Naples; he chairs the Naples Branch of SEMM (2003-2008). He has been member of the Scientific Advisory Board of the "Stazione Zoologica Anton Dohrn" of Naples from 1998 to 2007.

He has been visiting scientist or visiting professor for more than four years at several Institutions abroad: Argonne National Laboratory, Illinois, USA (Prof. Fritz Schlenk), Laboratoire de Biochimie Générale et Comparée, Collège de France, Paris, France (Prof. Jean Roche), European Molecular Biology Laboratory, Heidelberg, Germany (Proff. John Kendrew e Lenn Philippson), Department of Biological Science, University of Illinois, Chicago, Ill., USA (Prof. Stanley K.Shapiro), Department of Biochemistry, University of California, Berkeley, USA (Prof. Bruce Ames), Laboratory of Molecular Biology, Medical Research Council, Cambridge, UK (Prof. Sidney Brenner).

He is author of over 200 original papers published in the main journals the field of biomedicine. He is an Editor of Gene, and is Associate Editor or reviewer for various international journals in the field of biochemistry and molecular biology applied to clinical medicine.

He has also served as an expert member, president or coordinator on various national and international committees concerning scientific research and policy in the field of Biomedicine and Life Sciences.

He is member of different Scientific Societies and is, together with four Nobel prizes, member of the International Jury for assignment of the "Rey Jaime I" prize (Spain).

He received several prizes and acknowledgements both nationally and internationally, among which the Certificate of Excellence of the New York Medical College (NY,USA), the golden medal of the Academy of Sciences (detta dei XL), Rome, and the golden medal of the Italian Ministry of University and Scientific Research.





  • Fortunato G, Di Taranto MD, Bracale UM, Del Guercio L, Carbone F, Mazzaccara C, Morgante A, D’Armiento FP, D’Armiento M, Porcellini M, Sacchetti L, Bracale G, Salvatore F.
    Decreased Paraoxonase-2 Expression in Human Carotids Durino the Progression of Atherosclerosis.
    Arterioscler Thromb Vasc Biol 2008 Mar; 28(3)594-600

  • Di Noto R, Mirabelli P, Mariotti E, Sacchetti L, Pane F, Rotoli B, Lo Pardo C, Del Vecchio L, Mecucci C, Salvatore F.
    CMRL-T, a novel T-cell line showing asynchronous phenotype (CD34(+)/CD1a(-)/TCRalphabeta(+)) and dual T-cell receptor beta chain.
    Leukemia. 2006 Dec;20(12):2175-7

  • Scudiero O, Nardone G, Omodei D, Tatangelo F, Vitale DF, Salvatore F, Castaldo G.
    A mannose-binding lectin-defective haplotype is a risk factor for gastric cancer.
    Clin Chem. 2006 Aug;52(8):1625-7

  • Ciacci C, Gennarelli D, Esposito G, Tortora R, Salvatore F, Sacchetti L.
    Hereditary fructose intolerance and celiac disease: a novel genetic association.
    Clin Gastroenterol Hepatol. 2006 May;4(5):635-8

  • Iaccarino G, Ciccarelli M, Sorriento D, Galasso G, Campanile A, Santulli G, Cipolletta E, Cerullo V, Cimini V, Altobelli GG, Piscione F, Priante O, Pastore L, Chiariello M, Salvatore F, Koch WJ, Trimarco B.
    Ischemic neoangiogenesis enhanced by beta2-adrenergic receptor overexpression: a novel role for the endothelial adrenergic system.
    Circ Res. 2005; 97(11): 1182-9

  • Pane F, Cimino G, Izzo B, Camera A, Vitale A, Quintarelli C, Picardi M, Specchia G, Mancini M, Cuneo A, Mecucci C, Martinelli G, Saglio G, Rotoli B, Mandelli F, Salvatore F, Foa R; GIMEMA group.
    Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia.
    Leukemia. 2005;19(4):628-35

  • Esposito G, Vitagliano L, Cevenini A, Amelio T, Zagari A, Salvatore F.
    Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child.
    Blood. 2005 Jan 15;105(2):905-6

  • Esposito G, Santamaria R, Vitagliano L, Ieno L, Viola A, Fiori L, Parenti G, Zancan L, Zagari A, Salvatore F.
    Six novel alleles identified in Italian hereditary fructose intolerance patients enlarge the mutation spectrum of the aldolase B gene.
    Hum Mutat. 2004 Dec.; 24(6):534

  • Canani BR, Terrin G, Cirillo P, Castaldo G, Salvatore F, Cardillo G, Coruzzo A, Troncone R.
    Butyrate as an effective treatment of congenital chloride diarrhea.
    Gastroenterology. 2004 Aug.: 127:630-4

  • Frisso G, Carsana A, Tinto N, Calcagno G, Salvatore F, Sacchetti L.
    Direct detection of exon deletions/duplications in female carriers of and male patients with Duchenne/Becker muscular dystrophy.
    Clin Chem. 2004 Aug.; 50(8):1435-8

  • Iaccarino G, Ciccarelli M, Sorriento D, Cipolletta E, Cerullo V, Iovino GL, Paudice A, Elia A, Santulli G, Campanile A, Arcucci O, Pastore L, Salvatore F, Condorelli G, Trimarco B.
    AKT participates in endothelial dysfunction in hypertension.
    Circulation. 2004 Jun 1: 109(21):2587-93

  • Rosti G, Martinelli G, Bassi S, Amabile M, Trabacchi E, Giannini B, Cilloni D, Izzo B, De Vivo A, Testoni N, Cambrin GR, Bonifazi F, Soverini S, Luatti S, Gottardi E, Alberti D, Pane F, Salvatore F, Saglio G, Baccarani M; Study Committee.
    Italian Cooperat Molecular response to imatinib in late chronic-phase chronic myeloid leukemia.
    Blood. 2004 Mar 15;103(6):2284-90

  • Picardi M, Pane F, Quintarelli C, De Renzo A, Del Giudice A, De Divitiis B, Persico M, Ciancia R, Salvatore F, Rotoli B.
    Hepatitis B virus reactivation after fludarabine-based regimens for indolent non-Hodgkin's lymphomas: high prevalence of acquired viral genomic mutations.
    Haematologica. 2003 Nov;88(11):1296-303

  • Castaldo G, Tomaiuolo R, Sanduzzi A, Ponticiello A, Marchetiello I, Salvatore F.
    Carcinoembryonic antigen mRNA analysis detects micrometastatic cells in blood from lung cancer patients.
    Eur Respir J. 2003 Sep;22(3):418-21

  • Castaldo G, Nardiello P, Bellitti F, Rocino A, Coppola A, di Minno G, Salvatore F
    Denaturing HPLC procedure for factor IX gene scanning.
    Clin Chem. 2003 May;49(5):815-8

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